The Connection Between Joint Pain And Intestinal Bacteria

Can bacteria in the intestines cause joint pain? According to several studies, these microbes affect the immune system and trigger problems in other parts of the body.
The connection between joint pain and intestinal bacteria

Rheumatoid arthritis is caused by deterioration of the cartilage, which causes inflammation and joint pain. In today’s post, we will review the connection between joint pain and intestinal bacteria.

Joint pain and intestinal bacteria

Although researchers have identified some risk factors that could trigger this health problem, experts are still unsure of the direct cause of this disease.

In their search for the exact cause, a group of researchers has focused on a potential culprit that has never been taken into account so far: The bacteria that live in our intestines.

Recent studies have determined that bacteria in the gut can cause joint pain, including pain caused by rheumatoid arthritis.

In addition, they are related to diseases that alter the function of the immune system, leading to other chronic problems.

 Bacteria in the intestines, a cause of joint pain

In a 2013 study, a rheumatologist at New York University, Dr. José Scher found that patients with rheumatoid arthritis were more likely to have a bacterium in their gut called Prevotella COPRI than those who did not suffer from the disease.

In another study published in October of the same year, Scher found that those with psoriatic arthritis have lower levels of important bacteria in their intestines.

2-gut bacteria

These studies are part of an effort by researchers around the world. To understand and explain the role that the microbiome (the mass of microbes that live in the gastrointestinal tract) plays in general health.

It is believed that the intestinal flora consists of over 1000 different species of bacteria, which together weigh between 1 and 3 kilos. In recent years, scientists have tried to prove that these organisms have a lot to do with human health; some trigger disease while others protect the body.

Joint pain and intestinal bacteria: Bacteria in the intestines affect the immune system

Veena Taneja, an immunologist at the Mayo Clinic in Rochester, Minnesota, confirms that “ with each study, it becomes clearer that these microbes can affect the immune system and contribute to diseases beyond the gut. Joint pain is linked to bacteria in the intestines. ”


Researchers were surprised that  gut bacteria affect the immune system far more than first thought.

In recent decades, cases of autoimmune diseases have increased, and many microbiome researchers are convinced that modern lifestyles and the changes it has caused in the microbiome ecosystem are partly responsible for this problem.

Joint pain and intestinal bacteria: Prevotella COPRI  bacteria may be responsible for joint pain

These microbes affect the health of the intestines, where two thirds of the body’s immune cells are located. During digestion, the gastrointestinal tract struggles with a constant influx of foreign microbes that are ingested along with food and drink.

4-joint pain

To do their job, the intestines have developed a comprehensive immune system, which extends to other organs besides the intestines. The immune cells that live in the gut possess the ability to activate inflammatory cells across the entire body, including in the joints.

According to expert José Scher. Can Prevotella COPRI bacteria cause an immune reaction that later spreads to other tissues, causing joint pain. Another theory is that the beneficial microbes are displaced, which weakens the immune system.

The latest theory is one of the most supported, as a study showed that patients with high levels of Prevotella COPRI had reduced levels of bacteroides fragilis, which is a beneficial bacterium that supports the immune system.

The results of these studies have given rise to new studies, to create strategies to use bacteria as a treatment for immune diseases.

In fact , health experts already recommend probiotics (good bacteria), to restore the intestinal flora and treat health problems such as acne, insomnia and other problems that have been linked to intestinal health.

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